Short Answer: Man could not defy God if Man was made by God from nothing (that is ex nihilo).
Man could defy God only if there was some-thing in Man which was autonomous from God - some-thing that did the defying.
Yet Man does defy God (life is full of it; the Bible is full of it).
Therefore Man was NOT made by God from nothing, and there is Some-Thing in Man which is autonomous from God.
This is the only metaphysical assumption which makes plain sense of the fact that Man does indeed - really and truly - defy God.